Publikationen
Aktuelle Veröffentlichungen der KFO5002
- de Oliveira, Gaedcke, Haubrock, Beissbarth, Conradi; Effects of the Novel PFKFB3 Inhibitor KAN0438757 on Colorectal Cancer Cells and Its Systemic Toxicity Evaluation In Vivo, in Cancers 2021, 13(5), 1011;
- Ewers, Katharina M, Shilpa Patil, Waltraut Kopp, Jürgen Thomale, Tabea Quilitz,, Anna Magerhans, Xin Wang, Elisabeth Hessmann, Matthias Dobbelstein: HSP90 inhibition synergizes with cisplatin to eliminate basal-like pancreatic ductal adenocarcinoma cells.(accepted in: Cancers)
- Hessmann E, Schneider G; 1(st) Virtual Göttingen-Munich-Marburg Pancreatic Cancer Meeting. New Insights Into Pancreatic Cancer: Notes from a Virtual Meeting. Gastroenterology. 2021 Sep;161(3):785-791. doi: 10.1053/j.gastro.2021.04.082. Epub 2021 Jun 2. PMID: 34089734.
- Isermann T, Sener ÖC, Stender A, Klemke L, Winkler N, Neesse A, Li J, Wegwitz F, Moll UM and Schulz-Heddergott R. Suppression of HSF1 activity by wildtype p53 creates a driving force for p53 loss-of-heterozygosity. Nature Comm. 2021 Jun 29;12(1):4019. IF 12.2
- Klemke L, Fehlau CF, Winkler N, Toboll F, Singh SK, Moll UM and Schulz-Heddergott R. The gain-of-function p53 R248W allele promotes migration by STAT3 deregulation in human pancreatic cancer cells. Frontiers in Oncology. 2021 Jun 11;11:642603. IF 4.9
- Mengyu Tu, Lukas Klein, Elisa Espinet, Theodoros Georgomanolis, Florian Wegwitz, Xiaojuan Li, Laura Urbach, Adi Danieli-Mackay, Stefan Küffer, Kamil Bojarczuk, Athanasia Mizi, Ufuk Günesdogan, Björn Chapuy, Zuguang Gu, Albrecht Neesse, Uday Kishore, Philipp Ströbel, Elisabeth Hessmann, Stephan A. Hahn, Andreas Trumpp, Argyris Papantonis, Volker Ellenrieder & Shiv K. Singh TNF-α-producing macrophages determine subtype identity and prognosis via AP1 enhancer reprogramming in pancreatic cancer. Nat Cancer 2, 1185–1203 (2021). doi.org/10.1038/s43018-021-00258-w
- Patil S, Steuber B, Kopp W, Kari V, Urbach L, Wang X, Küffer S, Bohnenberger H, Spyropoulou D, Zhang Z, Versemann L, Bösherz MS, Brunner M, Gaedcke J, Ströbel P, Zhang JS, Neesse A, Ellenrieder V, Singh SK, Johnsen SA, Hessmann E. EZH2 Regulates Pancreatic Cancer Subtype Identity and Tumor Progression via Transcriptional Repression of GATA6. Cancer Res. 2020 Nov 1;80(21):4620-4632. doi: 10.1158/0008-5472.CAN-20-0672. Epub 2020 Sep 9. PMID: 32907838.
- Patil S, Forster T, Reutlinger K, Kopp W, Versemann L, Spitalieri J, Gaedcke J, Ströbel K, Singh SK, Ellenrieder V; Neesse A, Hessmann E: Chromatin-independent interplay of NFATc1 and EZH2 in pancreatic cancer. (accepted in: Cells)
- Versemann L, Hessmann E, Ulisse M: Epigenetic Therapeutic Strategies to target Molecular and Cellular Heterogeneity in Pancreatic Cancer, (in print) DOI: 10.1159/000519859 (Visceral Medicine)